irritability
noun/ˌɪrɪtəˈbɪlɪti/
Frequency rank: #16,300 most common English word
Meaning
the tendency to become easily annoyed or angry

Example sentence
After several sleepless nights, his irritability made it hard for anyone to talk to him.
Synonyms & related words
- grumpiness
- moodiness
- crankiness
- testiness
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