irreversible
adjective/ˌɪrɪˈvɜrsəbəl/
Frequency rank: #9,748 most common English word
Meaning
impossible to undo or reverse; permanent.

Example sentence
The damage caused by the oil spill was irreversible, and the ecosystem never fully recovered.
Synonyms & related words
- permanent
- unrecoverable
- irreparable
- lasting
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